Welcome to IB2
The Integrative Bioinformatics and Biostatistics group at RECETOX, Masaryk University, works at the intersection of computational pathology, microbiome research and cancer biostatistics.
Computational pathology and transcriptomics
We use deep learning for exploring whole slide images and combine the extracted features with molecular data for gaining new insights into the cancer universe. We were the first to demonstrate that molecular subtypes of colon cancer can be predicted using pathology images.
Microbiome and cancer
Linking the microbiome to tumor progression. The microbiome modulates the host immune response to cancer and plays a central role in tumor progression. Understanding these interactions may provide prognostic and predictive tools and hints towards novel therapeutic approaches.
Tumor heterogeneity
Bioinformatics explorations of intra-/inter-tumor heterogeneity. Both inter-tumor and intra-tumor heterogeneity are major obstacles towards precision medicine. We develop bioinformatics approaches combining various OMICS for shedding light on this complex universe.