IB2: Integrative Bioinformatics and Biostatistics
IB2: Integrative Bioinformatics and Biostatistics
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Impact of intrapartum antibiotic prophylaxis on the oral and fecal bacteriomes of children in the first week of life
Intrapartum antibiotic prophylaxis (IAP) is commonly used during C-section delivery and in Group B Streptococcus-positive women before …
Eliska Pivrncova
,
Lucie Buresova
,
Iva Kotaskova
,
Petra Videnska
,
Lenka Andryskova
,
Pavel Piler
,
Petr Janku
,
Ivo Borek
,
Jan Bohm
,
Barbara Lanickova
,
Jana Klanova
,
Eva Budinská
,
Petra Borilova Linhartova
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DOI
An invasion front gene expression signature for higher-risk patient selection in stage IIA MSS colon cancer
Stage II colon cancer (CC) encompasses a heterogeneous group of patients with diverse survival experiences: 87% to 58% 5-year relative …
Eva Budinská
,
Martina Hrivňáková
,
Tina Catela Ivkovič
,
Tana Machackova
,
Marie Boudna
,
Lucie Pifkova
,
Ondrej Slabý
,
Beatrix Bencsiková
,
Vlad Popovici
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Project
DOI
Molecular portraits of colorectal cancer morphological regions
Transcriptomics and tumor morphology are intertwined.
Eva Budinská
,
Martina Hrivňáková
,
Tina Catela Ivkovič
,
Marie Madrzyk
,
Rudolf Nenutil
,
Beatrix Bencsiková
,
Dagmar Al Tukmachi
,
Michaela Ručková
,
Lenka Dubska Zdražilová
,
Ondrej Slabý
,
Josef Feit
,
Mihnea-Paul Dragomir
,
Petra Borilova Linhartova
,
Sabine Tejpar
,
Vlad Popovici
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Project
DOI
Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study
Background Indoor dust particles are an everyday source of human exposure to microorganisms and their inhalation may directly affect …
Eva Konecna
,
Petra Videnska
,
Lucie Buresova
,
Milan Urik
,
Sona Smetanova
,
Stanislav Smatana
,
Roma Prokes
,
Barbara Lanickova
,
Eva Budinská
,
Jana Klanova
,
Petra Borilova Linhartova
PDF
DOI
IntOMICS: A Bayesian Framework for Reconstructing Regulatory Networks Using Multi-Omics Data
We provide the R implementation of
IntOMICS
Anna Pačinková
,
Vlad Popovici
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Project
DOI
Using empirical biological knowledge to infer regulatory networks from multi-omics data
We provide
IntOMICS
, a framework for multi-omics data integration using a novel approach to biological knowledge discovery.
Anna Pačinková
,
Vlad Popovici
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Project
DOI
Vegan Diet Is Associated With Favorable Effects on the Metabolic Performance of Intestinal Microbiota: A Cross-Sectional Multi-Omics Study
Background and Aim: Plant-based diets are associated with potential health benefits, but the contribution of gut microbiota remains to …
Magdalena Prochazkova
,
Eva Budinská
,
Marek Kuzma
,
Heleca Pelantova
,
Jaromir Hradecky
,
Marie Heczkova
,
Nikola Daskova
,
Miriam Bratova
,
Istvan Modos
,
Petra Videnska
,
Petra Splichalova
,
Solomon Sowah
,
Maria Kralova
,
Marina Henikova
,
Eliska Selinger
,
Krystof Klima
,
Karel Chalupsky
,
Radislav Sedlacek
,
Rikard Landberg
,
Tilman Kühn
,
Jan Gojda
,
Monika Cahova
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DOI
Colorectal tumour mucosa microbiome is enriched in oral pathogens and defines three subtypes that correlate with markers of tumour progression
Long-term dysbiosis of the gut microbiome has a significant impact on colorectal cancer (CRC) progression and explains part of the …
Barbora Zwinsová
,
Vyacheslav A. Petrov
,
Martina Hrivňáková
,
Stanislav Smatana
,
Lenka Micenková
,
Natálie Kzdová
,
Vlad Popovici
,
Roman Hrstka
,
Roman Šefr
,
Beatrix Bencsiková
,
Lenka Zdražilová-Dubská
,
Veronika Brychtová
,
Rudolf Nenutil
,
Petra Videnska
,
Eva Budinská
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Project
DOI
An explorative analysis of ABCG2/TOP-1 mRNA expression as a biomarker test for FOLFIRI treatment in stage III colon cancer patients: results from retrospective analyses of the PETACC-3 trial
Biomarker-guided treatment for patients with colon cancer is needed. We tested ABCG2 and topoisomerase 1 (TOP1) mRNA expression as …
Jan Stenvang
,
Eva Budinská
,
Eric van Cutsem
,
Fred Bosman
,
Vlad Popovici
,
Nils Brünner
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