IB2: Integrative Bioinformatics and Biostatistics
IB2: Integrative Bioinformatics and Biostatistics
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QBI SABI 2023
The Spatial Analysis for Biological Imaging workshop.
Vlad Popovici
Mar 27, 2023
1 min read
Importance of tumor sampling in transcriptomics-based risk stratification
Vlad Popovici
,
Tina Catela Ivkovič
,
Martina Hrivňáková
,
Michal Němeček
,
Rudolf Nenutil
,
Lenka Zdražilová-Dubská
,
Ondrej Slabý
,
Beatrix Bencsiková
,
Eva Budinská
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Project
Poster
The impact of tumour morphology landscape on molecular signatures
Eva Budinská
,
Tina Catela Ivkovič
,
Martina Hrivňáková
,
Rudolf Nenutil
,
Michal Němeček
,
Lenka Zdražilová-Dubská
,
Ondrej Slabý
,
Beatrix Bencsiková
,
Vlad Popovici
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Project
Poster
Molecular portraits of major morphological components of colon tumors
We investigate the molecular landscape of the morphotypes.
Vlad Popovici
Colorectal tumour mucosa microbiome is enriched in oral pathogens and defines three subtypes that correlate with markers of tumour progression
Long-term dysbiosis of the gut microbiome has a significant impact on colorectal cancer (CRC) progression and explains part of the …
Barbora Zwinsová
,
Vyacheslav A. Petrov
,
Martina Hrivňáková
,
Stanislav Smatana
,
Lenka Micenková
,
Natálie Kzdová
,
Vlad Popovici
,
Roman Hrstka
,
Roman Šefr
,
Beatrix Bencsiková
,
Lenka Zdražilová-Dubská
,
Veronika Brychtová
,
Rudolf Nenutil
,
Petra Videnska
,
Eva Budinská
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Project
DOI
Consensus molecular subtypes of morphological regions on colorectal tumors
Background
The consensus molecular subtypes (CMS) of colon cancer integrated the results of several different subtyping efforts and led …
Vlad Popovici
,
Tina Catela Ivkovič
,
Martina Hrivňáková
,
Rudolf Nenutil
,
Michal Němeček
,
Lenka Zdražilová-Dubská
,
Ondrej Slabý
,
Beatrix Bencsiková
,
Eva Budinská
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Project
Poster
An explorative analysis of ABCG2/TOP-1 mRNA expression as a biomarker test for FOLFIRI treatment in stage III colon cancer patients: results from retrospective analyses of the PETACC-3 trial
Biomarker-guided treatment for patients with colon cancer is needed. We tested ABCG2 and topoisomerase 1 (TOP1) mRNA expression as …
Jan Stenvang
,
Eva Budinská
,
Eric van Cutsem
,
Fred Bosman
,
Vlad Popovici
,
Nils Brünner
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Project
DOI
ONCOBIOME: Gut OncoMicrobiome Signatures associated with cancer incidence, prognosis and prediction of treatment response
Exploiting the gut microbiome for cancer diagnosis and treatment
Eva Budinská
Clinical implications of intra-tumour heterogeneity in colon cancer
Region-based biomarkers.
Vlad Popovici
Colobiome: Tumour-adjacent microbiome and immune profile of tumour in the context of heterogeneity and aggressivness of colorectal cancer
The aim is to improve prognostic and predictive stratification of CRC by defining microbial-immune-molecular CRC pathophenotypes and correlate them with tumour aggressiveness and patient prognosis.
Eva Budinská
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